Adaptogenic and Stress-Relieving Herbs in Mental Health
by Bombale Sarthak S., Ghule Sinare Akshay R., Kshirsagar Vaishnavi V., Sachin, K. Hodgar Sanket A.
Published: December 6, 2025 • DOI: 10.51584/IJRIAS.2025.101100026
Abstract
Mental health disorders such as stress, anxiety, and depression have become a major global concern, significantly affecting quality of life and productivity. Conventional pharmacological treatments, although effective, are often associated with adverse effects and long-term dependency. In recent years, adaptogenic and stress-relieving herbs have gained growing attention as safer, holistic alternatives in the management of mental health disorders. Adaptogens are natural substances that enhance the body’s resilience to physical, emotional, and environmental stressors by modulating the hypothalamic–pituitary–adrenal (HPA) axis and maintaining homeostasis. Herbs such as Withania somnifera (Ashwagandha), Bacopa monnieri (Brahmi), Ocimum sanctum (Tulsi), Panax ginseng (Ginseng), and Rhodiola rosea have demonstrated promising results in reducing stress, improving cognition, regulating neurotransmitter activity, and protecting against oxidative damage. Several clinical studies support their role in alleviating symptoms of anxiety, depression, and stress-related disorders, with minimal side effects. However, standardization, dosage optimization, and large-scale clinical validation remain challenges for their wider acceptance in modern medicine. This review aims to highlight the pharmacological mechanisms, therapeutic benefits, and clinical evidence of adaptogenic herbs in promoting mental well-being, thereby offering a natural and sustainable approach to mental health care.