Intriguing Biological Impact of Citric Acid Fruit Juices and its Combined Effect with Honey plus Spice Extract of Cinnamomum Verum (L)

Abstract

The purpose of this study was to examine the qualitative, quantitative estimation of phytocompounds, proximate composition and antibacterial activity also anticancer activity against the skin melanoma cancer cell lines of the three different citrus based fruit juices named as Citrus limon, (L.) Citrus × sinensis (l.), Phyllanthus emblica (Linn.) and its composition mixture of curd, honey and spice extract. Apart from the current research conclusion that above said all the property of the biological effect clearly denoted the main peak flavonoid and phenolic compounds such as Limonene, 3,3-Dimethyl-4-(3,3,4,4-tetra methyloxetan-2-ylidene) butan-2-one and 9-Octadecenoic acid (z) o elucidated by GCMS technique. Among the various compounds these three compounds possessed excellent pharmacological potential properties particularly against the pathogenic clinical organisms and skin melanoma cancer lines. Moreover, when subjected the highly potential mixed commodities of three fruit mixture with Honey showed a unique biological impact so the same sample treated with SKM cancer cell lines. After treted cell lines showed the remarkable apoptotic anticancer activity and DNA fragmentation assay. Therefore the present research was clearly denoted among the six various experimental samples mixture composition of specific commodity of Honey was a better potential biological effect has been reflected overall the framed objectives. Hence, the present work uniquely expressed these three Citrus-based fruit juices with honey substance is very potential for human health because rich in flavonoids and other bioactive compounds, exhibit promising anticancer activities, including the ability to inhibit cancer cell growth, induce apoptosis, and potentially prevent metastasis